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Molecular mechanism of Zn(2+) inhibition of a voltage-gated proton channel

Voltage-gated proton (Hv1) channels are involved in many physiological processes, such as pH homeostasis and the innate immune response. Zn(2+) is an important physiological inhibitor of Hv1. Sperm cells are quiescent in the male reproductive system due to Zn(2+) inhibition of Hv1 channels, but beco...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qiu, Feng, Chamberlin, Adam, Watkins, Briana M., Ionescu, Alina, Perez, Marta Elena, Barro-Soria, Rene, González, Carlos, Noskov, Sergei Y., Larsson, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056077/
https://ncbi.nlm.nih.gov/pubmed/27647906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604082113
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