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Subunit interactions during cooperative opening of voltage-gated proton channels

Voltage-gated proton (Hv1) channels are dimers, where each subunit has a separate permeation pathway. However, opening of the two pathways is highly cooperative. It is unclear how Hv1 channels open their permeation pathways, because Hv1 channels lack a classic pore domain. Using voltage clamp fluoro...

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Main Authors: Qiu, Feng, Rebolledo, Santiago, Gonzalez, Carlos, Larsson, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558936/
https://ncbi.nlm.nih.gov/pubmed/23352165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.12.021
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