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IN VITRO ORGANIC NITRATE BIOACTIVATION TO NITRIC OXIDE BY RECOMBINANT ALDEHYDE DEHYDROGENASE 3A1

Organic nitrates (ORNs) are commonly used anti-ischemic and anti-anginal agents, which serve as an exogenous source of the potent vasodilator nitric oxide (NO). Recently, both mitochondrial aldehyde dehydrogenase-2 (ALDH2) and cytosolic aldehyde dehydrogenase-1a1 (ALDH1A1) have been shown to exhibit...

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Detalhes bibliográficos
Main Authors: Lin, Shunxin, Page, Nathaniel A., Fung, Sun Mi, Fung, Ho-Leung
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895916/
https://ncbi.nlm.nih.gov/pubmed/24126018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2013.09.005
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