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Inhibition of mitochondrial aldehyde dehydrogenase by nitric oxide-mediated S-nitrosylation

Mitochondrial aldehyde dehydrogenase (ALDH2) is responsible for the metabolism of acetaldehyde and other toxic lipid aldehydes. Despite many reports about the inhibition of ALDH2 by toxic chemicals, it is unknown whether nitric oxide (NO) can alter the ALDH2 activity in intact cells or in vivo anima...

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Main Authors: Moon, Kwan-Hoon, Kim, Bong-Jo, Song, Byoung J.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350915/
https://ncbi.nlm.nih.gov/pubmed/16242127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2005.09.082
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