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Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP
The sodium-taurocholate (TC) cotransporting polypeptide (NTCP) facilitates bile formation by mediating sinusoidal Na(+)-TC cotransport. During sepsis-induced cholestasis, there is a decrease in NTCP-dependent uptake of bile acids and an increase in nitric oxide (NO) levels in hepatocytes. In rat hep...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043645/ https://ncbi.nlm.nih.gov/pubmed/21109590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00170.2010 |
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