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Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP

The sodium-taurocholate (TC) cotransporting polypeptide (NTCP) facilitates bile formation by mediating sinusoidal Na(+)-TC cotransport. During sepsis-induced cholestasis, there is a decrease in NTCP-dependent uptake of bile acids and an increase in nitric oxide (NO) levels in hepatocytes. In rat hep...

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Hlavní autoři: Schonhoff, Christopher M., Ramasamy, Umadevi, Anwer, M. Sawkat
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043645/
https://ncbi.nlm.nih.gov/pubmed/21109590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00170.2010
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