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Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice
We examined the direct involvement of endothelial nitric oxide (eNOS) in nitrate tolerance using eNOS knockout (eNOS (−/−)) and wild-type (eNOS (+/+)) mice. Animals were treated with either nitroglycerin (NTG, 20 mg kg(−1)s.c. 3×daily for 3 days) or vehicle (5% dextrose, D5W), and nitrate tolerance...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573162/ https://ncbi.nlm.nih.gov/pubmed/11815364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704532 |
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