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Thorough QT study of the effect of oral moxifloxacin on QT(c) interval in the fed and fasted state in healthy Japanese and Caucasian subjects
AIMS: The aims of this study were three-fold and were to (i) investigate the effect of food (fasted and fed state) on the degree of QT prolongation caused by moxifloxacin under the rigorous conditions of a TQT study, (ii) differentiate the effects on QT(c) that arise from changes in PK from those ar...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Blackwell Science Inc
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3895358/ https://ncbi.nlm.nih.gov/pubmed/23713767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12168 |
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