The Power of Phase I Studies to Detect Clinical Relevant QTc Prolongation: A Resampling Simulation Study

著者: Ferber, Georg, Lorch, Ulrike, Täubel, Jörg
出版年 Biomed Res Int (2015)

Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity

著者: Ferber, Georg, Fernandes, Sara, Täubel, Jörg
出版年 J Clin Pharmacol (2017)

Stability of the Effect of a Standardized Meal on QTc

著者: Täubel, Jörg, Fernandes, Sara, Ferber, Georg
出版年 Ann Noninvasive Electrocardiol (2016)

Three steps to writing adaptive study protocols in the early phase clinical development of new medicines

著者: Lorch, Ulrike, O’Kane, Martin, Taubel, Jorg
出版事項 2014

Burns after photodynamic therapy

著者: Hettiaratchy, Shehan, Clarke, John, Taubel, Jorg, Besa, Chola
出版事項 2000

Comparison of Digital 12‐Lead ECG and Digital 12‐Lead Holter ECG Recordings in Healthy Male Subjects: Results from a Randomized, Double‐Blinded, Placebo‐Controlled Clinical Trial...

著者: Wang, Duolao, Bakhai, Ameet, Arezina, Radivoj, Täubel, Jörg
出版年 Ann Noninvasive Electrocardiol (2016)

The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers

著者: Muirhead, Gary J, Faulkner, Stephen, Harness, Jane A, Taubel, Jörg
出版事項 2002

Safety, Tolerability, and Dose Proportionality of a Novel Transdermal Fentanyl Matrix Patch and Bioequivalence With a Matrix Fentanyl Patch: Two Phase 1 Single‐Center Open‐Label, R...

著者: Lorch, Ulrike, Pierscionek, Tomasz, Freier, Anne, Spencer, Christopher S., Täubel, Jörg
出版年 Clin Pharmacol Drug Dev (2020)

Pharmacokinetics, Safety and Cognitive Function Profile of Rupatadine 10, 20 and 40 mg in Healthy Japanese Subjects: A Randomised Placebo-Controlled Trial

著者: Täubel, Jörg, Ferber, Georg, Fernandes, Sara, Lorch, Ulrike, Santamaría, Eva, Izquierdo, Iñaki
出版年 PLoS One (2016)

Repeated supratherapeutic dosing of strontium ranelate over 15 days does not prolong QT(c) interval in healthy volunteers

著者: Taubel, Jorg, Naseem, Asif, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A. John
出版事項 2012

Thorough QT study of the effect of oral moxifloxacin on QT(c) interval in the fed and fasted state in healthy Japanese and Caucasian subjects

著者: Taubel, Jorg, Ferber, Georg, Lorch, Ulrike, Batchvarov, Velislav, Savelieva, Irina, Camm, A John
出版事項 2014

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising...

著者: Täubel, Jörg, Ferber, Georg, Lorch, Ulrike, Wang, Duolao, Sust, Mariano, Camm, A. John
出版年 PLoS One (2015)

Thorough QT study of the effect of intravenous amisulpride on QTc interval in Caucasian and Japanese healthy subjects

著者: Täubel, Jörg, Ferber, Georg, Fox, Gabriel, Fernandes, Sara, Lorch, Ulrike, Camm, A. John
出版年 Br J Clin Pharmacol (2016)

Pharmacokinetics, safety and tolerability of OBE022, a selective prostaglandin F2α receptor antagonist tocolytic: A first‐in‐human trial in healthy postmenopausal women

著者: Pohl, Oliver, Marchand, Line, Gotteland, Jean‐Pierre, Coates, Simon, Täubel, Jörg, Lorch, Ulrike
出版年 Br J Clin Pharmacol (2018)

Coadministration of the prostaglandin F2α receptor antagonist preterm labour drug candidate OBE022 with magnesium sulfate, atosiban, nifedipine and betamethasone

著者: Pohl, Oliver, Marchand, Line, Gotteland, Jean‐Pierre, Coates, Simon, Täubel, Jörg, Lorch, Ulrike
出版年 Br J Clin Pharmacol (2019)

Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials

著者: Coates, Simon, Wang, Duolao, Pierscionek, Tomasz, Fernandes, Sara, Djumanov, Dilshat, Lorch, Ulrike, Täubel, Jörg
出版年 Front Pharmacol (2020)

Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers

著者: Taubel, Jorg, Naseem, Asif, Harada, Tomohiko, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A John
出版事項 2010

Pharmacodynamic Consequences of Administration of VLA-4 Antagonist CDP323 to Multiple Sclerosis Subjects: A Randomized, Double-Blind Phase 1/2 Study

著者: Wolf, Christian, Sidhu, Jagdev, Otoul, Christian, Morris, Dexter L., Cnops, Jennifer, Taubel, Jorg, Bennett, Barbara
出版事項 2013

Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteers

著者: Taubel, Jorg, Lorch, Ulrike, Ferber, Georg, Singh, Jatinder, Batchvarov, Velislav N, Savelieva, Irina, Camm, A John
出版事項 2013

Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects

著者: Dixon, Ruth, Job, Sarah, Oliver, Ruth, Tompson, Debra, Wright, John G, Maltby, Kay, Lorch, Ulrike, Taubel, Jorg
出版事項 2008