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Stability of the Effect of a Standardized Meal on QTc

BACKGROUND: The assessment of QTc changes after the intake of a standardized meal has been proposed as an alternative approach to prove assay sensitivity when the proarrhythimic potential of a drug is to be excluded in either TQT or intensive Phase I QT studies. METHODS: In this article, an analysis...

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Bibliografiske detaljer
Udgivet i:Ann Noninvasive Electrocardiol
Main Authors: Täubel, Jörg, Fernandes, Sara, Ferber, Georg
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931674/
https://ncbi.nlm.nih.gov/pubmed/27233583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12371
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