Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects

AIMS: There is no consensus as to what extent the results of thorough QT interval/corrected QT interval (QT/QTc) studies need to be bridged. METHODS: The results of two studies using levofloxacin in Japanese and Caucasian subjects were compared in a post hoc analysis to investigate the similarity of...

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Detalhes bibliográficos
Main Authors: Sugiyama, Atsushi, Nakamura, Yuji, Nishimura, Satomi, Adachi-Akahane, Satomi, Kumagai, Yuji, Gayed, Juleen, Naseem, Asif, Ferber, Georg, Taubel, Jorg, Camm, John
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Drug Safety
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370350/
https://ncbi.nlm.nih.gov/pubmed/22442827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04110.x
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