The allometric exponent for scaling clearance varies with age: a study on seven propofol datasets ranging from preterm neonates to adults

AIM: For scaling clearance between adults and children, allometric scaling with a fixed exponent of 0.75 is often applied. In this analysis, we performed a systematic study on the allometric exponent for scaling propofol clearance between two subpopulations selected from neonates, infants, toddlers,...

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Bibliografske podrobnosti
Main Authors: Wang, Chenguang, Allegaert, Karel, Peeters, Mariska Y M, Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2014
Teme:
Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895356/
https://ncbi.nlm.nih.gov/pubmed/23772816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12180
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