CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1

The transcription factor NF-κB plays a key regulatory role in lymphocyte activation and generation of immune response. Stimulation of T cell receptor (TCR) induces phosphorylation of CARMA1 by PKCθ, resulting in formation of CARMA1-Bcl10-MALT1 (CBM) complex at lipid rafts and subsequently leading to...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Sakamoto, Takashi, Kobayashi, Masayuki, Tada, Kohei, Shinohara, Masanobu, Io, Katsuhiro, Nagata, Kayoko, Iwai, Fumie, Takiuchi, Yoko, Arai, Yasuyuki, Yamashita, Kouhei, Shindo, Keisuke, Kadowaki, Norimitsu, Koyanagi, Yoshio, Takaori-Kondo, Akifumi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894987/
https://ncbi.nlm.nih.gov/pubmed/24465689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085762
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы