Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

HSP90 is a molecular chaperone that associates with numerous substrate proteins called clients. It plays many important roles in human biology and medicine, but determinants of client recognition by HSP90 have remained frustratingly elusive. We systematically and quantitatively surveyed most human k...

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Detaylı Bibliyografya
Asıl Yazarlar: Taipale, Mikko, Krykbaeva, Irina, Koeva, Martina, Kayatekin, Can, Westover, Kenneth D., Karras, Georgios I., Lindquist, Susan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894786/
https://ncbi.nlm.nih.gov/pubmed/22939624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.047
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