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Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
HSP90 is a molecular chaperone that associates with numerous substrate proteins called clients. It plays many important roles in human biology and medicine, but determinants of client recognition by HSP90 have remained frustratingly elusive. We systematically and quantitatively surveyed most human k...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894786/ https://ncbi.nlm.nih.gov/pubmed/22939624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.047 |
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