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Binding-rebinding dynamics of proteins interacting non-specifically with a long DNA molecule

We investigate how non-specific interactions and unbinding-rebinding events give rise to a length-and conformation-dependent enhancement of the “macroscopic” dissociation time of proteins from a DNA, or in general for release of ligands initially bound to a long polymer. By numerically simulating re...

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Autori principali: Parsaeian, Azita, de la Cruz, Monica Olvera, Marko, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894571/
https://ncbi.nlm.nih.gov/pubmed/24229102
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