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Binding of MetJ repressor to specific and non-specific DNA and the effect of SAM on these interactions

We have used analytical ultracentrifugation to characterize the binding of the methionine repressor protein, MetJ, to synthetic oligonucleotides containing 0 to 5 specific recognition sites, called metboxes. For all lengths of DNA studied, MetJ binds more tightly to repeats of the consensus sequence...

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Detalhes bibliográficos
Main Authors: Augustus, Anne M., Sage, Harvey, Spicer, Leonard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891263/
https://ncbi.nlm.nih.gov/pubmed/20196619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902011f
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