Determination of protein–DNA binding constants and specificities from statistical analyses of single molecules: MutS–DNA interactions

Atomic force microscopy (AFM) is a powerful technique for examining the conformations of protein–DNA complexes and determining the stoichiometries and affinities of protein–protein complexes. We extend the capabilities of AFM to the determination of protein–DNA binding constants and specificities. T...

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Detalles Bibliográficos
Main Authors: Yang, Yong, Sass, Lauryn E., Du, Chunwei, Hsieh, Peggy, Erie, Dorothy A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182163/
https://ncbi.nlm.nih.gov/pubmed/16061937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki708
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