טוען...
Characterization of Intermediate Steps in Amyloid Beta (Aβ) Production under Near-native Conditions
Processing of the amyloid precursor protein (APP) by γ-secretase results in generation of Aβ peptides of different lengths ranging from 51 to 30 residues. Accumulation of Aβ and in particular Aβ42 is enhanced by familial Alzheimer disease (FAD) causing mutations in APP and is believed to play a pivo...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894335/ https://ncbi.nlm.nih.gov/pubmed/24225948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498246 |
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