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Two-Step Amyloid Aggregation: Sequential Lag Phase Intermediates

The self-assembly of proteins into fibrillar structures called amyloid fibrils underlies the onset and symptoms of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s. However, the molecular basis and mechanism of amyloid aggregation are not completely understood. For many amyloidogenic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Castello, Fabio, Paredes, Jose M., Ruedas-Rama, Maria J., Martin, Miguel, Roldan, Mar, Casares, Salvador, Orte, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220338/
https://ncbi.nlm.nih.gov/pubmed/28067252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40065
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