טוען...
The Small GTPase Arf6 Is Essential for the Tram/Trif Pathway in TLR4 Signaling
Recognition of lipopolysaccharides (LPS) by Toll-like receptor 4 (TLR4) at the plasma membrane triggers NF-κB activation through recruitment of the adaptor proteins Mal and MyD88. Endocytosis of the activated TLR4 allows recruitment of the adaptors Tram and Trif, leading to activation of the transcr...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894321/ https://ncbi.nlm.nih.gov/pubmed/24297182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.499194 |
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