High Fat and High Sucrose (Western) Diet Induce Steatohepatitis that is Dependent on Fructokinase

Fructose intake from added sugars has been implicated as a cause of nonalcoholic fatty liver disease. Here we tested the hypothesis that fructose may interact with high fat diet to induce fatty liver, and to determine if this was dependent on a key enzyme in fructose metabolism, fructokinase. Wild t...

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Autors principals: Ishimoto, Takuji, Lanaspa, Miguel A., Rivard, Christopher J., Roncal-Jimenez, Carlos A., Orlicky, David J., Cicerchi, Christina, McMahan, Rachel H., Abdelmalek, Manal F., Rosen, Hugo R., Jackman, Matthew R., MacLean, Paul S., Diggle, Christine P., Asipu, Aruna, Inaba, Shinichiro, Kosugi, Tomoki, Sato, Waichi, Maruyama, Shoichi, Sánchez-Lozada, Laura G., Sautin, Yuri Y., Hill, James O., Bonthron, David T., Johnson, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894259/
https://ncbi.nlm.nih.gov/pubmed/23813872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26594
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