Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment

BACKGROUND: Protein aggregation and the formation of intracellular inclusions are a central feature of many neurodegenerative disorders, but precise knowledge about their pathogenic role is lacking in most instances. Here we have characterized inclusions formed in transgenic mice carrying the P56S m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kuijpers, Marijn, van Dis, Vera, Haasdijk, Elize D, Harterink, Martin, Vocking, Karin, Post, Jan A, Scheper, Wiep, Hoogenraad, Casper C, Jaarsma, Dick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893532/
https://ncbi.nlm.nih.gov/pubmed/24252306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-24
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