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Inhibition by Siomycin and Thiostrepton of Both Aminoacyl-tRNA and Factor G Binding to Ribosomes

Siomycin, a peptide antibiotic that interacts with the 50S ribosomal subunit and inhibits binding of factor G, is shown also to inhibit binding of aminoacyl-tRNA; however, it does not impair binding of fMet-tRNA and completion of the initiation complex. Moreover, unlike other inhibitors of aminoacyl...

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Hlavní autoři: Ll, Juan Modole, Cabrer, Bartolomé, Parmeggiani, Andrea, Azquez, David V
Médium: Artigo
Jazyk:Inglês
Vydáno: 1971
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC389295/
https://ncbi.nlm.nih.gov/pubmed/4331558
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