Inhibition by Siomycin and Thiostrepton of Both Aminoacyl-tRNA and Factor G Binding to Ribosomes

Siomycin, a peptide antibiotic that interacts with the 50S ribosomal subunit and inhibits binding of factor G, is shown also to inhibit binding of aminoacyl-tRNA; however, it does not impair binding of fMet-tRNA and completion of the initiation complex. Moreover, unlike other inhibitors of aminoacyl...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Ll, Juan Modole, Cabrer, Bartolomé, Parmeggiani, Andrea, Azquez, David V
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1971
Fag:	Biological Sciences: Biochemistry
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4331558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.8.1796
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