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On the simultaneous association analysis of large genomic regions: a massive multi-locus association test

Motivation: For samples of unrelated individuals, we propose a general analysis framework in which hundred thousands of genetic loci can be tested simultaneously for association with complex phenotypes. The approach is built on spatial-clustering methodology, assuming that genetic loci that are asso...

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Detalhes bibliográficos
Main Authors: Qiao, Dandi, Cho, Michael H., Fier, Heide, Bakke, Per S., Gulsvik, Amund, Silverman, Edwin K., Lange, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892690/
https://ncbi.nlm.nih.gov/pubmed/24262215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt654
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