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On the Follow-Up of Genome-Wide Association Studies: An Overall Test for the Most Promising S.N.P.’s

Even in large-scale genome-wide association studies, only a fraction of the true associations are detected at the genome-wide significance level. When few or no associations reach the significance threshold, one strategy is to follow-up on the most promising candidates, i.e. the single nucleotide po...

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Detalhes bibliográficos
Main Authors: Lipman, Peter J., Cho, Michael H., Bakke, Per, Gulsvik, Amund, Kong, Xiangyang, Lomas, David, Anderson, Wayne, Silverman, Edwin, Lange, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096304/
https://ncbi.nlm.nih.gov/pubmed/21374717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20578
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