Loading...
PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies
To quantify polygenic effects, i.e. undetected genetic effects, in large-scale association studies, we propose a generalized estimating equation (GEE) based estimation framework. We develop a marginal model for single-variant association test statistics of complex diseases that generalizes existing...
Saved in:
| Published in: | Biostatistics |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2018
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5991211/ https://ncbi.nlm.nih.gov/pubmed/28968646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxx040 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|