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On the Recombination Rate Estimation in the Presence of Population Substructure

As recombination events are not uniformly distributed along the human genome, the estimation of fine-scale recombination maps, e.g. HapMap Project, has been one of the major research endeavors over the last couple of years. For simulation studies, these estimates provide realistic reference scenario...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hecker, Julian, Prokopenko, Dmitry, Lange, Christoph, Fier, Heide Löhlein
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696844/
https://ncbi.nlm.nih.gov/pubmed/26716445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145152
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