Functional coupling of chloride–proton exchanger ClC-5 to gastric H(+),K(+)-ATPase

It has been reported that chloride–proton exchanger ClC-5 and vacuolar-type H(+)-ATPase are essential for endosomal acidification in the renal proximal cells. Here, we found that ClC-5 is expressed in the gastric parietal cells which secrete actively hydrochloric acid at the luminal region of the gl...

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Bibliographische Detailangaben
Hauptverfasser: Takahashi, Yuji, Fujii, Takuto, Fujita, Kyosuke, Shimizu, Takahiro, Higuchi, Taiga, Tabuchi, Yoshiaki, Sakamoto, Hisato, Naito, Ichiro, Manabe, Koji, Uchida, Shinichi, Sasaki, Sei, Ikari, Akira, Tsukada, Kazuhiro, Sakai, Hideki
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892156/
https://ncbi.nlm.nih.gov/pubmed/24429108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20136205
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