Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets

Dietary NaCl depletion increases Na(+) absorption and K(+) secretion in the colon, but the mechanisms are not fully understood. In mice fed with NaCl-depleted diets, the expression of claudin-2 and -7 increased compared to those in control mice. Aldosterone (ALD) concentration was also increased. We...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Furukawa, Chisa, Ishizuka, Noriko, Hayashi, Hisayoshi, Fujii, Naoko, Manabe, Aya, Tabuchi, Yoshiaki, Matsunaga, Toshiyuki, Endo, Satoshi, Ikari, Akira
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610316/
https://ncbi.nlm.nih.gov/pubmed/28939904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12494-1
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