A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo

Mast cells are implicated in the pathogenesis of inflammatory and autoimmune diseases. However, this notion based on studies in mast cell-deficient mice is controversial. We therefore established an in vivo model for hyperactive mast cells by specifically ablating the NF-κB negative feedback regulat...

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Hlavní autoři: Heger, Klaus, Fierens, Kaat, Vahl, J. Christoph, Aszodi, Attila, Peschke, Katrin, Schenten, Dominik, Hammad, Hamida, Beyaert, Rudi, Saur, Dieter, van Loo, Geert, Roers, Axel, Lambrecht, Bart N., Kool, Mirjam, Schmidt-Supprian, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891641/
https://ncbi.nlm.nih.gov/pubmed/24453940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001762
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