A20: attractive without showing cleavage

A20 (also known as TNFAIP3) is a deubiquitinating enzyme (DUB) that ensures optimal immune responses in cells stimulated by cytokines, such as TNF and IL-1, or pathogen components, such as lipopolysaccharide. Deletion of A20 in mice results in multi-organ inflammation and death within 2 weeks 1. The...

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Detalhes bibliográficos
Main Authors: Verhelst, Kelly, van Loo, Geert, Beyaert, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196973/
https://ncbi.nlm.nih.gov/pubmed/24878850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439014
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