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Negative regulation of NF-κB and its involvement in rheumatoid arthritis

The transcription factor NF-κB plays crucial roles in the regulation of inflammation and mmune responses, and inappropriate NF-κB activity has been linked with many autoimmune and inflammatory diseases, including rheumatoid arthritis. Cells employ a multilayered control system to keep NF-κB signalli...

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Bibliographic Details
Main Authors: van Loo, Geert, Beyaert, Rudi
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218875/
https://ncbi.nlm.nih.gov/pubmed/21639951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3324
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