The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity

Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive so far. Here we identify the G protein-coupled receptor (GPCR) sphing...

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Hlavní autoři: Kempf, Anissa, Tews, Bjoern, Arzt, Michael E., Weinmann, Oliver, Obermair, Franz J., Pernet, Vincent, Zagrebelsky, Marta, Delekate, Andrea, Iobbi, Cristina, Zemmar, Ajmal, Ristic, Zorica, Gullo, Miriam, Spies, Peter, Dodd, Dana, Gygax, Daniel, Korte, Martin, Schwab, Martin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891622/
https://ncbi.nlm.nih.gov/pubmed/24453941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001763
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