The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity

Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive so far. Here we identify the G protein-coupled receptor (GPCR) sphing...

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Main Authors: Kempf, Anissa, Tews, Bjoern, Arzt, Michael E., Weinmann, Oliver, Obermair, Franz J., Pernet, Vincent, Zagrebelsky, Marta, Delekate, Andrea, Iobbi, Cristina, Zemmar, Ajmal, Ristic, Zorica, Gullo, Miriam, Spies, Peter, Dodd, Dana, Gygax, Daniel, Korte, Martin, Schwab, Martin E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891622/
https://ncbi.nlm.nih.gov/pubmed/24453941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001763
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