Neutralization of Nogo-A Enhances Synaptic Plasticity in the Rodent Motor Cortex and Improves Motor Learning in Vivo

The membrane protein Nogo-A is known as an inhibitor of axonal outgrowth and regeneration in the CNS. However, its physiological functions in the normal adult CNS remain incompletely understood. Here, we investigated the role of Nogo-A in cortical synaptic plasticity and motor learning in the uninju...

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Autors principals: Zemmar, Ajmal, Weinmann, Oliver, Kellner, Yves, Yu, Xinzhu, Vicente, Raul, Gullo, Miriam, Kasper, Hansjörg, Lussi, Karin, Ristic, Zorica, Luft, Andreas R., Rioult-Pedotti, Mengia, Zuo, Yi, Zagrebelsky, Marta, Schwab, Martin E.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147625/
https://ncbi.nlm.nih.gov/pubmed/24966370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3817-13.2014
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