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Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and λ repressors

Efficient and specific interactions between proteins bound to the same DNA molecule can be dependent on the length of the DNA tether that connects them. Measurement of the strength of this DNA tethering effect has been largely confined to short separations between sites, and it is not clear how it c...

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Detalhes bibliográficos
Main Authors: Priest, David G., Cui, Lun, Kumar, Sandip, Dunlap, David D., Dodd, Ian B., Shearwin, Keith E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890862/
https://ncbi.nlm.nih.gov/pubmed/24344307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317817111
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