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Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells

Eukaryotic gene regulation involves complex patterns of long-range DNA-looping interactions between enhancers and promoters, but how these specific interactions are achieved is poorly understood. Models that posit other DNA loops—that aid or inhibit enhancer–promoter contact—are difficult to test or...

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Bibliographische Detailangaben
Hauptverfasser: Priest, David G., Kumar, Sandip, Yan, Yan, Dunlap, David D., Dodd, Ian B., Shearwin, Keith E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210295/
https://ncbi.nlm.nih.gov/pubmed/25288735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410764111
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