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Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells

Eukaryotic gene regulation involves complex patterns of long-range DNA-looping interactions between enhancers and promoters, but how these specific interactions are achieved is poorly understood. Models that posit other DNA loops—that aid or inhibit enhancer–promoter contact—are difficult to test or...

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Autori principali: Priest, David G., Kumar, Sandip, Yan, Yan, Dunlap, David D., Dodd, Ian B., Shearwin, Keith E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210295/
https://ncbi.nlm.nih.gov/pubmed/25288735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410764111
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