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Enhancer-like long-range transcriptional activation by λ CI-mediated DNA looping

How distant enhancer elements regulate the assembly of a transcription complex at a promoter remains poorly understood. Here, we use long-range gene regulation by the bacteriophage λ CI protein as a powerful system to examine this process in vivo. A 2.3-kb DNA loop, formed by CI bridging its binding...

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Detalhes bibliográficos
Main Authors: Cui, Lun, Murchland, Iain, Shearwin, Keith E., Dodd, Ian B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581938/
https://ncbi.nlm.nih.gov/pubmed/23382214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221322110
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