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Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate

Highly purified cAMP-dependent protein phosphokinase from adrenal-cortical tissue contains cAMP-receptor activity. In activating the kinase, cAMP binds to the receptor and causes it to dissociate from its complex with the kinase. The kinase, freed of receptor, is fully activated and no longer stimul...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Gill, Gordon N., Garren, Leonard D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1971
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.786
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