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Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate

Highly purified cAMP-dependent protein phosphokinase from adrenal-cortical tissue contains cAMP-receptor activity. In activating the kinase, cAMP binds to the receptor and causes it to dissociate from its complex with the kinase. The kinase, freed of receptor, is fully activated and no longer stimul...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gill, Gordon N., Garren, Leonard D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.786
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