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Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate
Highly purified cAMP-dependent protein phosphokinase from adrenal-cortical tissue contains cAMP-receptor activity. In activating the kinase, cAMP binds to the receptor and causes it to dissociate from its complex with the kinase. The kinase, freed of receptor, is fully activated and no longer stimul...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1971
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.786 |
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