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Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate

Highly purified cAMP-dependent protein phosphokinase from adrenal-cortical tissue contains cAMP-receptor activity. In activating the kinase, cAMP binds to the receptor and causes it to dissociate from its complex with the kinase. The kinase, freed of receptor, is fully activated and no longer stimul...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gill, Gordon N., Garren, Leonard D.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1971
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.786
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