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Cyclic Adenosine Monophosphate Receptor: Loss of cAMP-Dependent DNA Binding Activity after Proteolysis in the Presence of Cyclic Adenosine Monophosphate
The cAMP receptor requires cAMP for DNA binding at pH 8.0 but shows cAMP-independent DNA binding at pH 6.0. Incubation of the cAMP receptor with proteolytic enzymes in the presence of cAMP results in loss of DNA-binding ability at pH 8, while it is still able to bind cAMP and DNA at pH 6. Incubation...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1973
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427049/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4354854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.9.2529 |
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