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Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells

Long Interspersed Elements (L1 elements) are biologically active retrotransposons that are capable of autonomous replication using their own reverse transcriptase (RT) enzyme. Expression of the normally repressed RT has been implicated in cancer cell growth. However, at present, little is known abou...

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Detalhes bibliográficos
Main Authors: Patnala, Radhika, Lee, Sung-Hun, Dahlstrom, Jane E., Ohms, Stephen, Chen, Long, Dheen, S. Thameem, Rangasamy, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889873/
https://ncbi.nlm.nih.gov/pubmed/24337508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-013-2812-7
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