Prognostic value of LINE-1 retrotransposon expression and its subcellular localization in breast cancer

Long interspersed nuclear element 1 (L1) belongs to a family of retrotransposons. Expression of the normally repressed L1 retrotransposons has been shown to induce genome instability by creating DNA double-stranded breaks and chromosomal rearrangements through the process of retrotransposition. At p...

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Bibliografiske detaljer
Main Authors: Chen, Long, Dahlstrom, Jane E., Chandra, Arin, Board, Philip, Rangasamy, Danny
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Preclinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473189/
https://ncbi.nlm.nih.gov/pubmed/23053642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2246-7
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