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The Rho Guanine Nucleotide Exchange Factor Syx Regulates the Balance of Dia and ROCK Activities To Promote Polarized-Cancer-Cell Migration

The role of RhoA in promoting directed cell migration has been complicated by studies showing that it is activated both in the front and the rear of migrating cells. We report here that the RhoA-specific guanine nucleotide exchange factor Syx is required for the polarity of actively migrating brain...

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書誌詳細
主要な著者: Dachsel, Justus C., Ngok, Siu P., Lewis-Tuffin, Laura J., Kourtidis, Antonis, Geyer, Rory, Johnston, Lauren, Feathers, Ryan, Anastasiadis, Panos Z.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889543/
https://ncbi.nlm.nih.gov/pubmed/24126053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00565-13
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