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Phosphorylation-mediated 14-3-3 Protein Binding Regulates the Function of the Rho-specific Guanine Nucleotide Exchange Factor (RhoGEF) Syx

Syx is a Rho-specific guanine nucleotide exchange factor (GEF) that localizes at cell-cell junctions and promotes junction stability by activating RhoA and the downstream effector Diaphanous homolog 1 (Dia1). Previously, we identified several molecules, including 14-3-3 proteins, as Syx-interacting...

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מידע ביבליוגרפי
Main Authors: Ngok, Siu P., Geyer, Rory, Kourtidis, Antonis, Storz, Peter, Anastasiadis, Panos Z.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585103/
https://ncbi.nlm.nih.gov/pubmed/23335514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.432682
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