VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx

Vascular endothelial growth factor (VEGF) and Ang1 (Angiopoietin-1) have opposing effects on vascular permeability, but the molecular basis of these effects is not fully known. We report in this paper that VEGF and Ang1 regulate endothelial cell (EC) junctions by determining the localization of the...

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Detalhes bibliográficos
Main Authors: Ngok, Siu P., Geyer, Rory, Liu, Miaoliang, Kourtidis, Antonis, Agrawal, Sudesh, Wu, Chuanshen, Seerapu, Himabindu Reddy, Lewis-Tuffin, Laura J., Moodie, Karen L., Huveldt, Deborah, Marx, Ruth, Baraban, Jay M., Storz, Peter, Horowitz, Arie, Anastasiadis, Panos Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529520/
https://ncbi.nlm.nih.gov/pubmed/23253477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207009
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