VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx

Vascular endothelial growth factor (VEGF) and Ang1 (Angiopoietin-1) have opposing effects on vascular permeability, but the molecular basis of these effects is not fully known. We report in this paper that VEGF and Ang1 regulate endothelial cell (EC) junctions by determining the localization of the...

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Hauptverfasser: Ngok, Siu P., Geyer, Rory, Liu, Miaoliang, Kourtidis, Antonis, Agrawal, Sudesh, Wu, Chuanshen, Seerapu, Himabindu Reddy, Lewis-Tuffin, Laura J., Moodie, Karen L., Huveldt, Deborah, Marx, Ruth, Baraban, Jay M., Storz, Peter, Horowitz, Arie, Anastasiadis, Panos Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529520/
https://ncbi.nlm.nih.gov/pubmed/23253477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207009
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