Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics

Development of RNAi-based therapeutics has the potential to revolutionize treatment options for a range of human diseases. However, as with gene therapy, a major barrier to progress is the lack of methods to achieve and measure efficient delivery for systemic administration. We have developed a posi...

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Detalhes bibliográficos
Main Authors: Stevenson, Mark, Carlisle, Robert, Davies, Ben, Preece, Chris, Hammett, Michelle, Liu, Wei-li, Fisher, Kerry David, Ryan, Amy, Scrable, Heidi, Seymour, Leonard William
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889190/
https://ncbi.nlm.nih.gov/pubmed/24253258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.63
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